Affiliation:
1. Department of Internal Medicine, Division of Rheumatology, Gulhane Training and Research Hospital University of Health Sciences Ankara Turkey
2. Department of Internal Medicine, Division of Haematology, Gulhane Training and Research Hospital University of Health Sciences Ankara Turkey
3. Department of Public Health, Gulhane School of Medicine University of Health Science Ankara Turkey
Abstract
AbstractIntroductionWe aimed to evaluate the characteristics of the patients with a rheumatologic disease who underwent TPE.MethodA single‐center, retrospective study was conducted between January 2016 and June 2023.ResultsTwenty patients with a median age of 51 years received a median of 6 TPE sessions. Concurrently, immunosuppressive therapy was administered to 18 (90%) of them. During the follow‐up period, 9 patients (45%) died. Creatinine (p = 0.001), C‐reactive protein (p = 0.001), sedimentation rate (p = 0.002), leukocyte (p = 0.003), thrombocyte (p = 0.003), and neutrophil (p = 0.003) counts was decreased after TPE. Similarly, in the ROC analysis of post TPE laboratory parameters, urea, creatinine, CRP, hemoglobin, platelets, and lymphocytes predicted mortality with areas under the curve values ranging from 0.747 to 0.869. In the Cox regression analysis for mortality, creatinine was predictive for mortality (p = 0.030), HR 1.59 (95% CI: 1.05–2.41).ConclusionIn rheumatologic conditions, TPE is beneficial to fill the gap until the effects of immunosuppressants become apparent.