Metabolic pharmacokinetics of early chronic alcohol consumption mediated by liver alcohol dehydrogenases 1 and 3 in mice

Author:

Okuda Takahisa1ORCID,Haseba Takeshi12,Katsuyama Midori1,Maruyama Motoyo3,Akimoto Toshio3,Igarashi Tsutomu4,Ohno Youkichi1

Affiliation:

1. Department of Legal Medicine; Nippon Medical School; Tokyo Japan

2. Department of Legal Medicine; Kanagawa Dental University; Kanagawa Japan

3. Division of Laboratory Animal Science; Nippon Medical School; Tokyo Japan

4. Department of Ophthalmology; Nippon Medical School; Tokyo Japan

Funder

Japan Society for the Promotion of Science (JSPS) KAKENHI Grant

Publisher

Wiley

Subject

Gastroenterology,Hepatology

Reference23 articles.

1. Alcohol-use disorders;Schuckit;Lancet,2009

2. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity;Cederbaum;Dig. Dis.,2010

3. Relationships between nutrition, alcohol use, and liver disease;Lieber;Alcohol Res. Health,2003

4. Steady-state kinetic properties of purified rat liver alcohol dehydrogenase: application to predicting alcohol elimination rates in vivo;Crabb;Arch. Biochem. Biophys.,1983

5. Ethanol metabolism, cirrhosis and alcoholism;Lieber;Clin. Chim. Acta,1997

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