Azathioprine and allopurinol: A two-edged interaction
Author:
Publisher
Wiley
Subject
Gastroenterology,Hepatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1440-1746.2010.06254.x/fullpdf
Reference16 articles.
1. 1 Anonymous. NSW Health Safety Notice. Allopurinol and Azathioprine. A Serious and Known Drug Interaction. 2009; 011/09: pp 1-2. Cited 11 Nov 2009. Available from URL: http://www.health.nsw.gov.au/resources/quality/sabs/pdf/sn20090507.pdf.
2. 6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease;Dubinsky;Gastroenterol,2002
3. Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides;Gardiner;Eur. J. Gastroenterol. Hepatol.,2008
4. Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine;Sparrow;Clin. Gastroenterol. Hepatol.,2007
5. Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine;Sparrow;Aliment. Pharmacol. Ther.,2005
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