Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation
Author:
Affiliation:
1. College of Pharmacy and Research Institute of Drug Development; Chonnam National University; Gwangju Korea
2. Department of Life Science and Global Top5 Research Program; Ewha Womans University; Seoul Korea
Funder
National Research Foundation of Korea
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12887/fullpdf
Reference21 articles.
1. Akt1 in osteoblasts and osteoclasts controls bone remodeling;Kawamura;PLoS One,2007
2. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1;Yamaguchi;Endocr Rev,2000
3. Regulation of skeletal development by the Runx family of transcription factors;Komori;J Cell Biochem,2005
4. SOX9 determines RUNX2 transactivity by directing intracellular degradation;Cheng;J Bone Miner Res,2010
5. Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression;Stein;Oncogene,2004
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