The functional relevance of somatic synonymous mutations in melanoma and other cancers

Author:

Gotea Valer1,Gartner Jared J.2,Qutob Nouar3,Elnitski Laura1,Samuels Yardena3

Affiliation:

1. Translational and Functional Genomics Branch; National Human Genome Research Institute; NIH; Bethesda MD USA

2. Surgery Branch; National Cancer Institute; NIH; Bethesda MD USA

3. Department of Molecular Cell Biology; Weizmann Institute of Science; Rehovot Israel

Funder

National Human Genome Research Institute

Israel Science Foundation

European Research Council

Knell Family

Peter and Patricia Gruber Award

Gideon Hamburger, Israel

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Reference139 articles.

1. A method and server for predicting damaging missense mutations;Adzhubei;Nat. Methods,2010

2. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1;Agrawal;Science,2011

3. Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma;Agrawal;Cancer Discov.,2012

4. A “G” to “A” mutation at position -1 of a 5′ splice site in a late infantile form of Tay-Sachs disease;Akli;J. Biol. Chem.,1990

5. Decoding mechanisms by which silent codon changes influence protein biogenesis and function;Bali;Int. J. Biochem. Cell Biol.,2015

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