The role of phacoemulsification surgery in the incidence rate of rhegmatogenous retinal detachment

Author:

Nielsen Birgitte Romme12ORCID,Alberti Mark1,Høgild Morten Lyng3,Bek Toke3ORCID,Thinggaard Benjamin Sommer456ORCID,Grauslund Jakob56ORCID,Christensen Ulrik12,la Cour Morten12

Affiliation:

1. Department of Ophthalmology Rigshospitalet – Glostrup Copenhagen Denmark

2. Faculty of Health Sciences University of Copenhagen Copenhagen Denmark

3. Department of Ophthalmology Aarhus University Hospital Aarhus Denmark

4. OPEN Data Explorative Data Network Odense University Hospital Odense Denmark

5. Department of Clinical Research University of Southern Denmark Odense Denmark

6. Department of Ophthalmology Odense University Hospital Odense Denmark

Abstract

AbstractPurposeTo investigate changes in the incidence rate of primary rhegmatogenous retinal detachment (RRD) surgery over time and to determine to what extent these changes can be attributed to pseudophakia.MethodsThis nationwide cohort study was based on national patient registries. The study population comprised individuals at risk of RRD aged 40 years and above from 2006 to 2021 in Denmark. The primary outcome was RRD incidence, and the exposure was phacoemulsification surgery. A chart review was conducted to validate and examine the lens status of the outcome.ResultsThe crude and age‐adjusted incidence rate of RRD in the Danish population increased significantly during the study period. The largest increase in RRD was seen in phakic RRD (phRRD) (65%), whereas pseudophakic RRD (pRRD) accounted for 35% of the total increase. A chart review revealed that 17% of phRRDs were misclassified as pseudophakic, resulting in pRRD accounting for a total of 45% of the increase in RRD. The prevalence of pseudophakia in Denmark grew significantly for all age groups and for both sexes (p = 10−6) from 2006 to 2021, but the 1‐year incidence of pRRD in the pseudophakic population was constant throughout the entire period.ConclusionThe incidence rate of RRD is continuing to increase in Denmark. The increase in phRRD remains undetermined, and while the risk of pRRD seemed to be constant during the study period, 45% of the overall increase in RRD could be attributed to the rise of a growing pseudophakic population.

Funder

Candys Foundation

Synoptik-Fonden

Helsefonden

Publisher

Wiley

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