Harnessing the potential of data‐driven strategies to optimise transfusion practice

Author:

Evans H. G.1ORCID,Murphy M. F.123ORCID,Foy R.4ORCID,Dhiman P.5ORCID,Green L.678ORCID,Kotze A.9ORCID,von Neree L.10,Palmer A. J.11ORCID,Robinson S. E.12ORCID,Shah A.13ORCID,Tomini F.14ORCID,Trompeter S.1015ORCID,Warnakulasuriya S.1015ORCID,Wong W. K.16ORCID,Stanworth S. J.123ORCID

Affiliation:

1. NIHR Blood and Transplant Research Unit in Data Driven Transfusion Practice, Radcliffe Department of Medicine University of Oxford Oxford UK

2. Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital Oxford UK

3. NHS Blood and Transplant John Radcliffe Hospital Oxford UK

4. Leeds Institute of Health Sciences University of Leeds Leeds UK

5. Centre for Statistics in Medicine Botnar Research Centre Oxford UK

6. Blizard Institute Queen Mary University of London London UK

7. Barts Health NHS Trust London UK

8. NHS Blood and Transplant London UK

9. Leeds Teaching Hospitals Leeds UK

10. University College London Hospitals NHS Foundation Trust London UK

11. Nuffield Orthopaedic Centre Oxford University NHS Foundation Trust Oxford UK

12. Guy's and St Thomas' NHS Foundation Trust London UK

13. Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK

14. Queen Mary University of London London UK

15. University College London London UK

16. Cambridge University Hospitals NHS Foundation Trust Cambridge UK

Abstract

SummaryNo one doubts the significant variation in the practice of transfusion medicine. Common examples are the variability in transfusion thresholds and the use of tranexamic acid for surgery with likely high blood loss despite evidence‐based standards. There is a long history of applying different strategies to address this variation, including education, clinical guidelines, audit and feedback, but the effectiveness and cost‐effectiveness of these initiatives remains unclear. Advances in computerised decision support systems and the application of novel electronic capabilities offer alternative approaches to improving transfusion practice. In England, the National Institute for Health and Care Research funded a Blood and Transplant Research Unit (BTRU) programme focussing on ‘A data‐enabled programme of research to improve transfusion practices’. The overarching aim of the BTRU is to accelerate the development of data‐driven methods to optimise the use of blood and transfusion alternatives, and to integrate them within routine practice to improve patient outcomes. One particular area of focus is implementation science to address variation in practice.

Funder

National Institute for Health and Care Research

Publisher

Wiley

Subject

Hematology

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