Decreased tissue factor pathway inhibitor (TFPI)-dependent anticoagulant capacity in patients with cirrhosis who have decreased protein S but normal TFPI plasma levels

Author:

Potze Wilma1,Arshad Freeha1,Adelmeijer Jelle1,Blokzijl Hans2,van den Berg Arie P.2,Meijers Joost C. M.3,Porte Robert J.4,Lisman Ton

Affiliation:

1. Surgical Research Laboratory; University of Groningen; University Medical Centre Groningen; Groningen; The Netherlands

2. Department of Gastroenterology; University of Groningen; University Medical Centre Groningen; Groningen; The Netherlands

3. Department of Experimental Vascular Medicine; Academic Medical Centre; University of Amsterdam; Amsterdam; The Netherlands

4. Section of Hepatobiliary Surgery and Liver Transplantation; Department of Surgery; University of Groningen; University Medical Centre Groningen; Groningen; The Netherlands

Publisher

Wiley

Subject

Hematology

Reference29 articles.

1. Natural anticoagulants can be useful predictors of severity in chronic liver disease;Abdo;Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis,2010

2. Inhibitor of the factor VIIa-tissue factor complex is reduced in patients with disseminated intravascular coagulation but not in patients with severe hepatocellular disease;Bajaj;The Journal of Clinical Investigation,1987

3. Cultured normal human hepatocytes do not synthesize lipoprotein-associated coagulation inhibitor: evidence that endothelium is the principal site of its synthesis;Bajaj;Proceedings of the National Academy of Sciences of the USA,1990

4. Plasma protein S-antigen (PS:Ag) in selected disease states;Brudasca;Romanian Journal of Internal Medicine = Revue Roumaine De Medecine Interne,1994

5. Regulation of coagulation by protein S;Castoldi;Current Opinion in Hematology,2008

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