CB1 receptors down-regulate a cAMP/Epac2/PLC pathway to silence the nerve terminals of cerebellar granule cells
Author:
Affiliation:
1. Departamento de Bioquímica; Facultad de Veterinaria; Universidad Complutense; Madrid Spain
2. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos; Madrid Spain
Funder
Spanish ‘MINECO’
Instituto de Salud Carlos III
Comunidad de Madrid
Spanish MECD
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.14059/fullpdf
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3. Recruitment of new sites of synaptic transmission during the cAMP-dependent late phase of LTP at CA3-CA1 synapses in the hippocampus;Bolshakov;Neuron,1997
4. Epac proteins: multi-purpose cAMP targets;Bos;Trends Biochem. Sci.,2006
5. Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis;Branham;J. Biol. Chem.,2009
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