Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine-Reference-Cited by-同舟云学术

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

Published:2021-05-31 Issue:4 Volume:14 Page:1490-1504
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Diouf Barthelemy¹,Wing Claudia²,Panetta John C.¹,Eddins Donnie³,Lin Wenwei⁴,Yang Wenjian¹,Fan Yiping⁵,Pei Deqing⁶,Cheng Cheng⁶,Delaney Shannon M.²,Zhang Wei⁷,Bonten Erik J.¹,Crews Kristine R.¹,Paugh Steven W.¹,Li Lie¹,Freeman Burgess B.⁸,Autry Robert J.¹,Beard Jordan A.¹,Ferguson Daniel C.¹,Janke Laura J.⁹,Ness Kirsten K.¹⁰,Chen Taosheng⁴,Zakharenko Stanislav S.³,Jeha Sima¹¹,Pui Ching‐Hon¹¹,Relling Mary V.¹,Eileen Dolan M.²,Evans William E.¹

Affiliation:

1. Hematological Malignancies Program and Department of Pharmaceutical Sciences St. Jude Children’s Research Hospital Memphis Tennessee USA

2. Section of Hematology/Oncology Department of Medicine University of Chicago Chicago Illinois USA

3. Department of Developmental Neurobiology St. Jude Children’s Research Hospital Memphis Tennessee USA

4. Department of Chemical Biology and Therapeutics St. Jude Children’s Research Hospital Memphis Tennessee USA

5. Department of Computational Biology St. Jude Children’s Research Hospital Memphis Tennessee USA

6. Department of Biostatistics St. Jude Children’s Research Hospital Memphis Tennessee USA

7. Department of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA

8. Preclinical Pharmacokinetics Shared Resource St. Jude Children’s Research Hospital Memphis Tennessee USA

9. Department of Pathology St. Jude Children’s Research Hospital Memphis Tennessee USA

10. Department of Epidemiology and Cancer Control St. Jude Children’s Research Hospital Memphis Tennessee USA

11. Department of Oncology St. Jude Children’s Research Hospital Memphis Tennessee USA

Funder

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.13012

Reference50 articles.

1. Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects

2. Exploring molecular approaches in Amyotrophic lateral sclerosis: drug targets from clinical and pre‐clinical findings [published online ahead of print April 27, 2020);Alam M;Curr Molec Pharmacol

3. The neuromyopathy of vincristine in man

4. Vincristine pharmacokinetics after repetitive dosing in children

5. Peripheral neuropathy in children and adolescents treated for cancer

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