Comparison of Pharmacokinetics and Tissue Distribution Kinetics of Roxithromycin and Expression of CYP 3A1 between Pregnant Mice and Foetuses

Author:

Qin Yi1,Xu Weizhe1,Mo Lanjian2,Li Xiaorong1,Ge Beikang1,Xiong Jie1,Gao Lifang3,Xu Pinxiang1,Xue Ming1

Affiliation:

1. Department of Pharmacology; Beijing Laboratory for Biomedical Detection Technology and Instrument; School of Basic Medical Sciences; Capital Medical University; Beijing China

2. Guangxi Health Technical Vocational College; Nanning Guangxi China

3. Center for Food and Drug Safety Evaluation; Capital Medical University; Beijing China

Funder

National Foundation of Natural Sciences of China

Key Project for Academic Human Resources Development in Institutions of High Learning under the Jurisdiction of Beijing Municipality

Beijing Laboratory for Biomedical Detection Technology

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference26 articles.

1. The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin;Heikkinen;BJOG,2000

2. Pharmacokinetics in pregnancy;Dawes;Best Pract Res Clin Obstet Gynaecol,2001

3. Pharmacokinetics of Metformin during Pregnancy;Eyal;Drug Metab Dispos,2010

4. Pharmacokinetics in pregnancy; Clinical significance;Koren;J Popul Ther Clin Pharmacol,2011

5. Fentanyl pharmacokinetics in pregnant sheep after intravenous and transdermal administration to the ewe;Emma;Basic Clin Pharmacol Toxicol,2015

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