Unconventional T-cell recognition of an arthritogenic epitope of proteoglycan aggrecan released from degrading cartilage
Author:
Affiliation:
1. Institute of Cellular Medicine; Newcastle University; Newcastle upon Tyne UK
2. Institute for Cell and Molecular Biosciences; Newcastle University; Newcastle upon Tyne UK
Funder
Nuffield Foundation
Arthritis Research UK
JGW Patterson Foundation
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/imm.12557/fullpdf
Reference59 articles.
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3. Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule;Allen;J Immunol,1985
4. Antigenic competition at the level of peptide-Ia binding;Babbitt;Proc Natl Acad Sci U S A,1986
5. Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope;Allen;Nature,1987
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1. Expeditious Synthesis of a Glycopeptide Library;European Journal of Organic Chemistry;2022-08
2. Citrullinated Aggrecan Epitopes as Targets of Autoreactive CD 4+ T Cells in Patients With Rheumatoid Arthritis;Arthritis & Rheumatology;2019-03-08
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