Mechanism of Methotrexate-sensitivity of Choriocarcinoma Cells in Culture

Author:

Indue Takami,Nagura Eiichi,Toyoda Tetsuya,Ishizuka Takao,Gotoh Setsuko,Kawashima Kohei,Tomoda Yutaka,Nagai Yoshiyuki

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference26 articles.

1. Expression of Dihydrofolate Reductase and Thymidylate Synthase Genes in Mammalian Cells

2. Selective multiplication of dihydrofolate reductase genes in metho-trexate-resistant variants of cultured murine cells;Alt;J. Biol. Chem.,1978

3. On the nature of the transport alteration determing resistance to amethopterin in L1210 leukemia;Sirotnak;Cancer Res.,1968

4. Relative frequency and kinetic properties of transport-defective phenotypes among methotexate-resistant L1210 clonal cell lines derived in vivo;Sirotnak;Cancer Res.,1981

5. Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate;Flintoff;Biochemistry,1980

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