Successful definitive radiation treatment of refractory canine oral papillomatosis

Author:

Szczepanek Anett1,Bertran Judith1,Shiomitsu Keijiro1,Thorsen Lily1,Gutti Jishnu Rao1,Santoro Domenico1,Takada Marilia1ORCID

Affiliation:

1. Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida Gainesville Florida USA

Abstract

AbstractThis case report describes a three‐year‐old male intact border collie diagnosed with canine papillomavirus type 1 (CPV‐1+) oral papillomas resistant to standard‐of‐care. With time, he developed lesions consistent with squamous cell carcinoma. Malignant tumors were incompletely excised and treated with definitive external beam radiation therapy (45 Gy, 3 Gy × 15 daily). The remaining oral cavity received 27 Gy (1.8 Gy x 15 daily) to treat the disseminated oral papillomatosis. A temporary treatment delay of 2 weeks was instituted due to grade 3 mucositis. The patient remained in complete remission after 10 months from radiotherapy. No tumor recurrences were noted by the owners after >1 year from treatment.

Publisher

Wiley

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