Immunosuppressive treatment for autoimmune blistering diseases does not impair production of neutralizing antibodies after “booster” dose of COVID‐19 vaccine

Author:

Russo Roberto12,Capurro Niccolὸ12,Cozzani Emanuele12,Gasparini Giulia12,Canepa Paola12,Parodi Aurora12

Affiliation:

1. DISSAL ‐ Section of Dermatology University of Genoa Genoa Italy

2. San Martino IRCCS Polyclinic Hospital Genoa Italy

Abstract

AbstractSince vaccines against COVID‐19 are available, it has been debated if immunosuppressed patients with autoimmune blistering diseases (AIBDs) should be advised to interrupt the immunosuppressive therapy before receiving the vaccine, with consequent risk to experience a flare of disease. In the present study, we measured the neutralizing antibodies production after anti‐SARS‐CoV‐2 vaccination in patients with AIBDs on immunosuppressive treatment, compared to healthy controls. Our results give strength to the hypothesis that these patients do not need to discontinue their therapy to produce effective levels of neutralizing antibodies, in other words to achieve successful protection.

Publisher

Wiley

Subject

Dermatology

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