Pharmacokinetics and pharmacodynamics of three dosages of oestriol after continuous vaginal ring administration for 21 days in healthy, postmenopausal women

Author:

Oliveira Filho Raimundo Vieira de1,Antunes Natalícia de Jesus1ORCID,Ilha Jaime de Oliveira2,Moreno Ronilson Agnaldo1,Wedemeyer Ralph‐Steven3,Warnke André3,De Nucci Gilberto14

Affiliation:

1. Department of Pharmacology, Faculty of Medical SciencesState University of Campinas (UNICAMP) Campinas SP Brazil

2. Galeno Research Unit Campinas Brazil

3. SocraTec R&D GmbH Oberursel Germany

4. Department of PharmacologyInstitute of Biomedical Sciences, University of São Paulo São Paulo SP Brazil

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference26 articles.

1. The endocrine transition around menopause - a five years prospective study with profiles of gonadotropines, estrogens, androgens and SHBG among healthy women

2. Pharmacology of estrogens and progestogens: influence of different routes of administration

3. The effects of postmenopausal hormone therapy on serum estrogen, progesterone, and sex hormone‐binding globulin levels in healthy postmenopausal women;Edlefsen KL;Menopause,2010

4. Hormone replacement therapy in postmenopausal women;Yasui T;J Med Invest,2003

5. Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate

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