Impact of climate change on atopic dermatitis: A review by the International Eczema Council

Author:

Wang Sheng‐Pei1ORCID,Stefanovic Nicholas2ORCID,Orfali Raquel L.3ORCID,Aoki Valeria3ORCID,Brown Sara J.4ORCID,Dhar Sandipan5ORCID,Eichenfield Lawrence F.6ORCID,Flohr Carsten7ORCID,Ha Alex1ORCID,Mora Camilo8ORCID,Murase Jenny E.19ORCID,Rosenbach Misha10ORCID,Srinivas Sahana M.11ORCID,Thyssen Jacob P.12ORCID,Wei Maria L.113ORCID,Irvine Alan D.2ORCID,Abuabara Katrina1ORCID

Affiliation:

1. Department of Dermatology University of California San Francisco San Francisco California USA

2. Clinical Medicine Trinity College Dublin Dublin Ireland

3. Department of Dermatology, Faculdade de Medicina FMUSP Universidade de Sao Paulo Sao Paulo Brazil

4. Centre for Genomic & Experimental Medicine Institute of Genetics and Cancer, University of Edinburgh Edinburgh UK

5. Department of Pediatric Dermatology Institute of Child Health Kolkata India

6. Departments of Dermatology and Pediatrics University of California San Diego San Diego California USA

7. Unit for Population‐Based Dermatology Research, St John's Institute of Dermatology Guy's & St Thomas' NHS Foundation Trust and King's College London London UK

8. Department of Geography and Environment University of Hawai'i at Mānoa Honolulu Hawai'i USA

9. Department of Dermatology Palo Alto Foundation Medical Group Mountain View California USA

10. Department of Dermatology University of Pennsylvania Philadelphia Pennsylvania USA

11. Department of Dermatology Indira Gandhi Institute of Child Health Bengaluru India

12. Department of Dermatology and Venereology Bispebjerg Hospital, University of Copenhagen Copenhagen Denmark

13. Dermatology Service San Francisco VA Health Care System San Francisco California USA

Abstract

AbstractAtopic dermatitis (AD), the most burdensome skin condition worldwide, is influenced by climatic factors and air pollution; however, the impact of increasing climatic hazards on AD remains poorly characterized. Leveraging an existing framework for 10 climatic hazards related to greenhouse gas emissions, we identified 18 studies with evidence for an impact on AD through a systematic search. Most climatic hazards had evidence for aggravation of AD the impact ranged from direct effects like particulate matter‐induced AD exacerbations from wildfires to the potential for indirect effects like drought‐induced food insecurity and migration. We then created maps comparing the past, present, and future projected burden of climatic hazards to global AD prevalence data. Data are lacking, especially from those regions most likely to experience more climatic hazards. We highlight gaps important for future research: understanding the synergistic impacts of climatic hazards on AD, long‐term disease activity, the differential impact on vulnerable populations, and how basic mechanisms explain population‐level trends.

Publisher

Wiley

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