Alloimmunization risk associated with amino acid 223 substitution in the RhD protein: analysis in the light of molecular modeling

Author:

de Brevern Alexandre G.123ORCID,Floch Aline2456,Barrault Aurélie4,Martret Jennifer4,Bodivit Gwellaouen245,Djoudi Rachid4,Pirenne France2456ORCID,Tournamille Christophe245

Affiliation:

1. INSERM UMR_S 1134; Univ. Paris Diderot, Sorbonne Paris Cité, Univ. de la Réunion, Univ. Antilles; Paris

2. Laboratory of Excellence GR-Ex; Paris

3. Institut National de la Transfusion Sanguine (INTS); Paris

4. Etablissement Français du Sang Ile de France; Créteil France

5. IMRB-INSERM U955 Team 2 “Transfusion et Maladies du Globule Rouge”; Créteil France

6. UPEC; Université Paris Est-Créteil; Créteil France

Funder

Etablissement Français du Sang

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Reference64 articles.

1. The Rhesus site;Wagner;Transfus Med Hemother,2014

2. Variants of RhD--current testing and clinical consequences;Daniels;Br J Haematol,2013

3. Weak D alleles express distinct phenotypes;Wagner;Blood,2000

4. Alloimmunization to the D antigen by a patient with weak D type 21;McGann;Immunohematology,2010

5. D variants at the RhD vestibule in the weak D type 4 and Eurasian D clusters;Flegel;Transfusion,2009

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