Pregnane X receptor- andCYP3A4-humanized mouse models and their applications
Author:
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.2010.01129.x/fullpdf
Reference51 articles.
1. Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity;Cheng;Drug Metab Dispos,2009
2. Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation;Cheng;J Pharmacol Exp Ther,2010
3. Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice;Cheung;J Pharmacol Exp Ther,2006
4. Computational discovery of novel low micromolar human pregnane X receptor antagonists;Ekins;Mol Pharmacol,2008
5. Challenges predicting ligand-receptor interactions of promiscuous proteins: the nuclear receptor PXR;Ekins;PloS Comput Biol,2009
Cited by 39 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Nuclear Receptors and Stress Response Pathways Associated with the Development of Oral Mucositis Induced by Antineoplastic Agents;Pharmaceuticals;2024-08-20
2. Activation of PXR causes drug interactions with Paxlovid in transgenic mice;Acta Pharmaceutica Sinica B;2023-11
3. Determination of Regulation of Drug Metabolizing Enzymes and Transporters;Oral Bioavailability and Drug Delivery;2023-10-10
4. Use of Data from Transgenic Animals in Safety Pharmacology;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2023
5. Xenobiotic Receptor‐Mediated Gene Regulation in Drug Metabolism and Disposition;Drug Metabolism Handbook;2022-11-18
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3