An integrated approach to identify normal tissue expression of targets for antibody-drug conjugates: case study of TENB2
Author:
Affiliation:
1. Genentech Research and Early Development; South San Francisco; CA; USA
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.2012.02138.x/fullpdf
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3. The pharmacologic basis for antibody-auristatin conjugate activity;Alley;J Pharmacol Exp Ther,2009
4. Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates;Austin;Proc Natl Acad Sci U S A,2005
5. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites;Bai;J Biol Chem,1990
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