1. Department of Anaesthesia and Peri‐operative Medicine West Suffolk NHS Foundation Trust Bury St Edmunds, Suffolk UK
2. Anaesthesia and Critical Care Medicine, Southampton National Institute for Health Research (NIHR) Biomedical Research Centre University Hospitals Southampton NHS Foundation Trust / University of Southampton Southampton UK
3. Gastrointestinal Surgery, Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre Nottingham University Hospitals NHS Trust and University of Nottingham, Queen's Medical Centre Nottingham UK
4. David Greenfield Human Physiology Unit,MRCVersus Arthritis Centre for Musculoskeletal Ageing, School of Life Sciences University of Nottingham Queen's Medical Centre Nottingham UK