Type 4 Phosphodiesterase Inhibitors Have Clinical and In Vitro Anti-inflammatory Effects in Atopic Dermatitis

Author:

Hanifin Jon M.,Chan Sai C.,Cheng John B.,Tofte Susan J.,Henderson William R.,Kirby Deborah S.,Weiner Ethan S.

Publisher

Elsevier BV

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference22 articles.

1. Multiple isozymes of cyclic nucleotide phosphodiesterase;Beavo;Adv Cyc Nuc Res,1988

2. Cyclic Nucleotide Phosphodiesterases: Structure, Regulation and Drug Action. Multiple Phosphodiesterase Isoenzymes: Background, Nomenclature and Implications;Beavo,1990

3. Increased leukocyte histamine release with elevated cyclic AMP-phosphodiesterase activity in atopic dermatitis;Butler;J Allergy Clin lmmunol,1983

4. Differential inhibitor effects on cyclic AMP phosphodiesterase isotorms in atopic and normal leukocytes;Chan;J Lab Clin Med,1993

5. Altered prostaglandin E2 regulation of cytokine production in atopic dermatitis;Chan;J Immunol,1993

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