Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in the horse

Author:

Rezende M. L.1,Grimsrud K. N.2,Stanley S. D.3,Steffey E. P.3,Mama K. R.1

Affiliation:

1. Department of Clinical Sciences; College of Veterinary Medicine and Biomedical Sciences; Colorado State University; Fort Collins CO USA

2. Campus Veterinary Services; School of Veterinary Medicine; University of California; Davis CA USA

3. K.L. Maddy Equine Analytical Chemistry Laboratory; California Animal Health and Food Safety Laboratory; School of Veterinary Medicine; University of California; Davis CA USA

Funder

College Research Council, Colorado State University

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference41 articles.

1. Dexmedetomidine, a novel alpha2 -adrenergic agonist. A review of its pharmacodynamic characteristics;Aantaa;Drugs of the Future,1993

2. Pharmacological characterization of the hyperglycemia induced by alpha-2 adrenoceptor agonists;Angel;The Journal of Pharmacology and Experimental Therapeutics,1988

3. Cardiopulmonary effects of a two hour medetomidine infusion and its antagonism by atipamezole in horses and ponies;Bettschart-Wolfensberger;Journal of Veterinary Anaesthesia,1999a

4. Pharmacokinetics of medetomidine in ponies and elaboration of a medetomidine infusion regime which provides a constant level of sedation;Bettschart-Wolfensberger;Research in Veterinary Science,1999b

5. Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies;Bettschart-Wolfensberger;Equine Veterinary Journal,2005

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