Anti-protein C antibodies are associated with resistance to endogenous protein C activation and a severe thrombotic phenotype in antiphospholipid syndrome
Author:
Affiliation:
1. Haemostasis Research Unit; Department of Haematology; University College London; London UK
2. Department of Haematology; University College London Hospitals NHS Foundation Trust; London UK
Funder
LUPUS UK
Bayer Healthcare
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.12722/fullpdf
Reference37 articles.
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3. Peptide bond cleavages and loss of functional activity during inactivation of factor Va and factor VaR506Q by activated protein C;Nicolaes;J Biol Chem,1995
4. Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism;Rodeghiero;Ann Intern Med,1999
5. Acquired activated protein C resistance is associated with lupus anticoagulants and thrombotic events in pediatric patients with systemic lupus erythematosus;Male;Blood,2001
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