LPS‐induced inflammation desensitizes hepatocytes to Fas‐induced apoptosis through Stat3 activation—The effect can be reversed by ruxolitinib-Reference-Cited by-同舟云学术

LPS‐induced inflammation desensitizes hepatocytes to Fas‐induced apoptosis through Stat3 activation—The effect can be reversed by ruxolitinib

Published:2020-02-05 Issue:5 Volume:24 Page:2981-2992
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J Cell Mol Med

Author:

Markotic Antonio¹²^ORCID,Flegar Darja¹³,Grcevic Danka¹³,Sucur Alan¹³,Lalic Hrvoje³,Turcic Petra⁴,Kovacic Natasa¹⁵,Lukac Nina¹⁵,Pravdic Danijel⁶⁷,Vukojevic Katarina⁸⁹,Cavar Ivan⁶⁷,Kelava Tomislav¹³⁶

Affiliation:

1. Laboratory for Molecular Immunology Croatian Institute for Brain Research School of Medicine University of Zagreb Zagreb Croatia

2. Center for Clinical Pharmacology University Clinical Hospital Mostar Mostar Bosnia and Herzegovina

3. Department of Physiology School of Medicine University of Zagreb Zagreb Croatia

4. Department of Pharmacology Faculty of Pharmacy and Biochemistry University of Zagreb Zagreb Croatia

5. Department of Anatomy School of Medicine University of Zagreb Zagreb Croatia

6. Department of Physiology School of Medicine University of Mostar Mostar Bosnia and Herzegovina

7. University Clinical Hospital Mostar Mostar Bosnia and Herzegovina

8. Department of Anatomy, Histology and Embryology School of Medicine University of Split Split Croatia

9. Department of Medical Genetics School of Medicine University of Mostar Mostar Bosnia and Herzegovina

Funder

Federalno Ministarstvo Obrazovanja i Nauke

Hrvatska Zaklada za Znanost

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.14930

Reference47 articles.

1. Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner

2. TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation

3. IL-1β and TNFα Differentially Influence NF-κB Activity and FasL-Induced Apoptosis in Primary Murine Hepatocytes During LPS-Induced Inflammation

4. Tumor necrosis factor α prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: Role of nuclear factor-κB

5. Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

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