Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology

Author:

Simpson Julie E.1,Ince Paul G.1,Minett Thais23,Matthews Fiona E.45,Heath Paul R.1,Shaw Pamela J.1,Goodall Emily1,Garwood Claire J.1,Ratcliffe Laura E.1,Brayne Carol2,Rattray Magnus16,Wharton Stephen B.1,

Affiliation:

1. Sheffield Institute for Translational Neuroscience; University of Sheffield; Sheffield UK

2. Institute of Public Health; University of Cambridge; Cambridge UK

3. Department of Radiology; University of Cambridge; Cambridge UK

4. MRC Biostatistics Unit; Institute of Public Health; Cambridge UK

5. Institute of Health and Society; University of Newcastle; Newcastle UK

6. Faculty of Life Sciences; University of Manchester; Manchester UK

Funder

Medical Research Council

ARUK

Department of Health and the Medical Research Council

UK NIHR Biomedical Research Centre for Ageing and Age-related Disease Award

NIHR Cambridge Biomedical Research Centre

The Cambridgeshire and Peterborough NIHR CLAHRC

Nottingham University Hospitals NHS Trust

University of Sheffield

Sheffield Teaching Hospitals NHS Foundation Trust

Oxford Biomedical Research Centre

The Walton Centre NHS Foundation Trust, Liverpool

Publisher

Wiley

Subject

Physiology (medical),Neurology (clinical),Neurology,Histology,Pathology and Forensic Medicine

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