Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers-Reference-Cited by-同舟云学术

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Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers

Published:2015-11-23 Issue:1 Volume:46 Page:7-14
ISSN:0014-2972
Container-title:European Journal of Clinical Investigation
language:en
Short-container-title:Eur J Clin Invest

Author:

Hobl Eva-Luise¹,Reiter Birgit²,Schoergenhofer Christian¹,Schwameis Michael¹,Derhaschnig Ulla¹,Kubica Jacek³,Stimpfl Thomas²,Jilma Bernd¹

Affiliation:

1. Department of Clinical Pharmacology; Medical University of Vienna; Vienna Austria

2. Department of Laboratory Medicine; Medical University of Vienna; Vienna Austria

3. Department of Cardiology and Internal Medicine; Collegium Medicum; Nicolaus Copernicus University; Bydgoszcz Poland

Funder

Investigator Sponsored Study Programme of AstraZeneca

Publisher

Wiley

Subject

Clinical Biochemistry,Biochemistry,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/eci.12550/fullpdf

Reference36 articles.

1. Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: a platelet inhibition and patient outcomes (PLATO) trial subgroup analysis;Steg;Circulation,2010

2. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines;O'Gara;Circulation,2013

3. Benefit of clopidogrel in patients with acute coronary syndromes without ST-segment elevation in various risk groups;Budaj;Circulation,2002

4. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial;Chen;Lancet,2005

5. Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study;Sabatine;JAMA,2005

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2. Evaluating the pharmacokinetic and pharmacodynamic impact of different modes of ticagrelor administration;Expert Opinion on Drug Metabolism & Toxicology;2023-10-24

3. Negative Impact of ST-Segment Elevation Myocardial Infarction and Morphine Dose on Ticagrelor Uptake and Pharmacodynamics: A Population PK/PD Analysis of Pooled Individual Participant Data;Clinical Pharmacokinetics;2023-04-25

4. Analgesic drug use in patients with STEMI: Current perspectives and challenges;Frontiers in Medicine;2023-03-22

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