Active Suppression of Diabetes after Oral Administration of Insulin Is Determined by Antigen Dosage

Author:

BERGEROT I.,FABIEN N.,MAYER A.,THIVOLET C.

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference14 articles.

1. Oral tolerance: Immunologic mechanisms and treatment of animal and human organ specific autoimmune diseases by oral administration of autoantigens;Weiner;Annu. Rev. Immunol.,1994

2. Breeding of a non-obese diabetic strain of mice;Makino;Exp. Anim.,1980

3. Type 1 diabetes: a chronic autoimmune disease of human, mouse and rat;Castano;Annu. Rev. Immunol.,1990

4. CD8+ T-cell homing to the pancreas in the non-obese diabetic mouse is CD4+ T-cell- dependent;Thivolet;J. Immunol.,1991

5. Suppression of diabetes in nonobese diabetetic mice by oral administration of porcine insulin;Zhang;Proc. Natl. Acad. Sci. USA,1991

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