A novel dual glucagon-like peptide and glucagon receptor agonist SAR425899: Results of randomized, placebo-controlled first-in-human and first-in-patient trials

Author:

Tillner Joachim1,Posch Maximilian G.2,Wagner Frank2,Teichert Lenore3,Hijazi Youssef1,Einig Christine3,Keil Stefanie4,Haack Torsten4,Wagner Michael4,Bossart Martin4,Larsen Philip J.4

Affiliation:

1. Translational Medicine; Sanofi; Frankfurt Germany

2. Charité Research Organisation GmbH; Berlin Germany

3. R&D Clinical Sciences; Sanofi; Frankfurt Germany

4. R&D Diabetes Division; Sanofi; Frankfurt Germany

Funder

Sanofi

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference42 articles.

1. World Health Organization http://www.who.int/mediacentre/factsheets/fs311/en/

2. Rate and risk predictors for development of self-reported type-2 diabetes mellitus over a 5-year period: the SHIELD study;Rodbard;Int J Clin Pract,2012

3. Prevalence and outcomes of comorbid metabolic and cardiovascular conditions in middle- and older-age adults;Oldridge;J Clin Epidemiol,2001

4. World Health Organization http://www.who.int/mediacentre/factsheets/fs312/en/

5. Harnessing glucagon-like peptide-1 receptor agonists for the pharmacological treatment of overweight and obesity;Burcelin;Obes Rev,2017

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