An Overview of SSR149415, a Selective Nonpeptide Vasopressin V1b Receptor Antagonist for the Treatment of Stress-Related Disorders

Author:

Gal Claudine Serradeil-Le,Wagnon Jean,Tonnerre Bernard,Roux Richard,Garcia Georges,Griebel Guy,Aulombard Alain

Publisher

Wiley

Subject

Pharmacology,Neuropsychology and Physiological Psychology

Reference39 articles.

1. Vasopressinergic regulation of the hypothalamic-pituitary-adrenal axis: Implications for stress adaptation;Aguilera;Regul Pept,2000

2. Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression;Alonso;Mol Psychiatry,2003

3. Molecular pharmacology of AVP and OT receptors and therapeutic potential;Barberis;Int Drug Newsmag Drug News Persp,1999

4. Blanchard R Griebel G Gully D et al. Effect of the V 1b receptor antagonist, SSR149415 and the CRF1 receptor antagonist, SSR125543a in the V 1b suggest antidepressant-like activity Soc Neurosci Meeting 2002 307.3

5. Blanchard R Griebel G Yang M Markham C Farrokhi C Blanchard D. The V 1b receptor antagonist SSR149415 reduces aggressive behaviors in hamsters Soc Neurosci 2003 217.3

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