Photo-co-carcinogenesis of Topically Applied Retinyl Palmitate in SKH-1 Hairless Mice

Author:

Boudreau Mary D.1,Beland Frederick A.1,Felton Robert P.2,Fu Peter P.1,Howard Paul C.3,Mellick Paul W.4,Thorn Brett T.2,Olson Greg R.4

Affiliation:

1. Division of Biochemical Toxicology; Food and Drug Administration; National Center for Toxicological Research; Jefferson Arkansas

2. Division of Bioinformatics and Biostatistics; Food and Drug Administration; National Center for Toxicological Research; Jefferson Arkansas

3. Office of Scientific Coordination; Food and Drug Administration; National Center for Toxicological Research; Jefferson Arkansas

4. Jefferson Laboratories; Toxicologic Pathology Associates, Inc.; Jefferson Arkansas

Funder

Interagency Agreement (IAG)

U.S. Food and Drug Administration

National Center for Toxicological Research

U.S. Department of Health and Human Services

National Institute of Environmental Health Sciences

National Toxicology Program

National Institutes of Health

Publisher

Wiley

Subject

Physical and Theoretical Chemistry,General Medicine,Biochemistry

Reference74 articles.

1. The biological effects of retinoids on cell differentiation and proliferation;Favennec;J. Clin. Chem. Clin. Biochem.,1988

2. Topical retinoids in skin ageing: A focused update with reference to sun-induced epidermal vitamin A deficiency;Sorg;Dermatology,2014

3. Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes;Kurlandsky;J. Biol. Chem.,1996

4. Retinoid metabolism in the skin;Roos;Pharmacol. Rev.,1998

5. Retinol and retinyl ester epidermal pools are not identically sensitive to UVB irradiation and anti-oxidant protective effect;Sorg;Dermatology,1999

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