Prognostic impact of CRTC1/3‐MAML2 fusions in salivary gland mucoepidermoid carcinoma: A multiinstitutional retrospective study

Author:

Okumura Yoshihide12,Nakano Satsuki1,Murase Takayuki1,Ueda Kaori12,Kawakita Daisuke3,Nagao Toshitaka4,Kusafuka Kimihide5,Urano Makoto6,Yamamoto Hidetaka7ORCID,Kano Satoshi8,Tsukahara Kiyoaki9,Okami Kenji10,Nagao Toru2,Hanai Nobuhiro11,Iwai Hiroshi12,Kawata Ryo13,Tada Yuichiro14,Nibu Ken‐Ichi15,Inagaki Hiroshi1ORCID

Affiliation:

1. Department of Pathology and Molecular Diagnostics Graduate School of Medical Sciences Nagoya City University Nagoya Japan

2. Department of Maxillofacial Surgery School of Dentistry Aichi‐Gakuin University Nagoya Japan

3. Department of Otolaryngology, Head and Neck Surgery Graduate School of Medical Sciences Nagoya City University Nagoya Japan

4. Department of Anatomic Pathology Tokyo Medical University Tokyo Japan

5. Department of Pathology Shizuoka General Hospital Shizuoka Japan

6. Department of Diagnostic Pathology School of Medicine Fujita Health University Toyoake Japan

7. Department of Anatomic Pathology Graduate of School of Medical Science Kyushu University Fukuoka Japan

8. Department of Otolaryngology‐Head and Neck Surgery Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan

9. Department of Otorhinolaryngology, Head and Neck Surgery Tokyo Medical University Tokyo Japan

10. Department of Otolaryngology‐Head and Neck Surgery Tokai University School of Medicine Isehara Japan

11. Department of Head and Neck Surgery Aichi Cancer Center Hospital Nagoya Japan

12. Department of Otolaryngology, Head and Neck Surgery Kansai Medical University Hirakata Japan

13. Department of Otorhinolaryngology‐Head and Neck Surgery Osaka Medical College Takatsuki Japan

14. Department of Head and Neck Oncology and Surgery International University of Health and WelfareMita Hospital Tokyo Japan

15. Department of Otolaryngology‐Head and Neck Surgery Kobe University Graduate School of Medicine Kobe Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference38 articles.

1. Prognostic factors in mucoepidermoid carcinoma of the salivary glands

2. Mucoepidermoid carcinoma: a five-decade journey

3. NCCN Clinical Practice Guidelines in Oncology Head and Neck Cancers version 1.2020; accessed April 18. Available from:https://www.nccn.org/professionals/physician_gls/PDF/head‐and‐neck.pdf

4. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway

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