Elevating the significance of legume intake: A novel strategy to counter aging‐related mitochondrial dysfunction and physical decline

Author:

Zheng Qingwei1,Wang Feijie1,Nie Chenzhipeng1,Zhang Kuiliang1,Sun Yujie1,AL‐Ansi Waleed1,Wu Qiming2,Wang Li1ORCID,Du Jun2,Li Yan1ORCID

Affiliation:

1. State Key Laboratory of Food Science and Technology, School of Food Science and Technology Jiangnan University Wuxi China

2. Nutrilite Health Institute Shanghai China

Abstract

AbstractMitochondrial dysfunction increasingly becomes a target for promoting healthy aging and longevity. The dysfunction of mitochondria with age ultimately leads to a decline in physical functions. Among them, biogenesis dysfunction and the imbalances in the metabolism of reactive oxygen species and mitochondria as signaling organelles in the aging process have aroused our attention. Dietary intervention in mitochondrial dysfunction and physical decline during aging processes is essential, and greater attention should be directed toward healthful legume intake. Legumes are constantly under investigation for their nutritional and bioactive properties, and their consumption may yield antiaging and mitochondria‐protecting benefits. This review summarizes mitochondrial dysfunction with age, discusses the benefits of legumes on mitochondrial function, and introduces the potential role of legumes in managing aging‐related physical decline. Additionally, it reveals the benefits of legume intake for the elderly and offers a viable approach to developing legume‐based functional food.

Funder

Qinglan Project of Jiangsu Province of China

Ministry of Science and Technology of the People's Republic of China

Publisher

Wiley

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