Radiation therapy for ventricular arrhythmias

Author:

Liulu Xingzhou1ORCID,Balaji Poornima23ORCID,Barber Jeffrey45ORCID,De Silva Kasun23ORCID,Murray Tiarne4ORCID,Hickey Andrew4ORCID,Campbell Timothy23ORCID,Harris Jill4ORCID,Gee Harriet45ORCID,Ahern Verity45ORCID,Kumar Saurabh235ORCID,Hau Eric4567,Qian Pierre C235ORCID

Affiliation:

1. Cardiology Department Royal North Shore Hospital Sydney New South Wales Australia

2. Cardiology Department, Westmead Hospital University of Sydney Sydney New South Wales Australia

3. Westmead Applied Research Centre, Faculty of Medicine and Health University of Sydney Sydney New South Wales Australia

4. Department of Radiation Oncology, Crown Princess Mary Cancer Centre Westmead Hospital Sydney New South Wales Australia

5. Sydney Medical School, University of Sydney Sydney New South Wales Australia

6. Translational Radiation Biology and Oncology Laboratory, Centre for Cancer Research The Westmead Institute for Medical Research Sydney New South Wales Australia

7. Blacktown Hematology and Cancer Centre, Blacktown Hospital Blacktown New South Wales Australia

Abstract

AbstractVentricular arrhythmias (VA) can be life‐threatening arrhythmias that result in significant morbidity and mortality. Catheter ablation (CA) is an invasive treatment modality that can be effective in the treatment of VA where medications fail. Recurrence occurs commonly following CA due to an inability to deliver lesions of adequate depth to cauterise the electrical circuits that drive VA or reach areas of scar responsible for VA. Stereotactic body radiotherapy is a non‐invasive treatment modality that allows volumetric delivery of energy to treat circuits that cannot be reached by CA. It overcomes the weaknesses of CA and has been successfully utilised in small clinical trials to treat refractory VA. This article summarises the current evidence for this novel treatment modality and the steps that will be required to bring it to the forefront of VA treatment.

Funder

Heart Foundation

National Health and Medical Research Council

Publisher

Wiley

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Getting to the heart of the matter;Journal of Medical Imaging and Radiation Oncology;2024-08-29

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