The association between immigration status and the development of type 2 diabetes in women with a prior diagnosis of gestational diabetes: A population‐based study

Author:

Ho Jessica S. S.1,Read Stephanie H.23,Giannakeas Vasily23,Sarma Shohinee456,Berger Howard7,Feig Denice S.3456ORCID,Fleming Karen8,Ray Joel G.3567,Rosella Laura39,Shah Baiju R.35610ORCID,Lipscombe Lorraine L.2356ORCID

Affiliation:

1. School of Medicine Queen's University Kingston Ontario Canada

2. Women's College Research Institute Women's College Hospital Toronto Ontario Canada

3. ICES Toronto Ontario Canada

4. Leadership Sinai Center for Diabetes Mount Sinai Hospital Toronto Ontario Canada

5. Department of Medicine University of Toronto Toronto Ontario Canada

6. Institute of Health Policy, Management and Evaluation University of Toronto Toronto Ontario Canada

7. Department of Obstetrics and Gynecology St. Michael's Hospital Toronto Ontario Canada

8. Department of Family and Community Medicine Sunnybrook Health Sciences Centre Toronto Ontario Canada

9. Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada

10. Department of Medicine Sunnybrook Health Sciences Centre Toronto Ontario Canada

Abstract

AbstractAimsThe aim of this study was to examine the influence of immigration status and region of origin on the risk of type 2 diabetes in women with prior gestational diabetes (GDM).MethodsThis retrospective population‐based cohort study included women with gestational diabetes (GDM) aged 16 to 50 years in Ontario, Canada, who gave birth between 2006 and 2014. We compared the incidence of type 2 diabetes after delivery between long‐term residents and immigrants—overall, by time since immigration and by region of—using Cox regression adjusted for age, year, neighbourhood income, rurality, infant birth weight and presence of hypertensive disorders of pregnancy (HDP).ResultsAmong 38,515 women with prior GDM (42% immigrants), immigrants had a significantly higher risk of type 2 diabetes compared with long‐term residents (adjusted hazard ratio [HR] 1.19, 95% confidence interval [CI] 1.13–1.26), with no meaningful difference based on time since immigration. The highest adjusted relative risks of type 2 diabetes compared with long‐term residents were found for immigrants from Sub‐Saharan Africa (HR 1.63, 95% CI 1.40–1.90), Latin America/Caribbean (HR 1.44, 95% CI 1.28–1.62) and South Asia (HR 1.34, 95% CI 1.25–1.44).ConclusionsImmigration is associated with a significantly higher risk of type 2 diabetes after GDM, particularly for women from certain low‐ and middle‐income countries. Diabetes prevention strategies will need to consider the unique needs of immigrants from these regions.

Funder

Institute for Clinical Evaluative Sciences

Physicians' Services Incorporated Foundation

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

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