A double point mutation at residues Ile14 and Val15 of Bcl‐2 uncovers a role for the BH4 domain in both protein stability and function-Reference-Cited by-同舟云学术

A double point mutation at residues Ile14 and Val15 of Bcl‐2 uncovers a role for the BH4 domain in both protein stability and function

Published:2017-12-02 Issue:1 Volume:285 Page:127-145
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Monaco Giovanni¹,La Rovere Rita¹,Karamanou Spyridoula²,Welkenhuyzen Kirsten¹,Ivanova Hristina¹,Vandermarliere Elien³,Di Martile Marta⁴,Del Bufalo Donatella⁴,De Smedt Humbert¹,Parys Jan B.¹,Economou Anastassios²,Bultynck Geert¹

Affiliation:

1. Laboratory of Molecular and Cellular Signaling Department of Cellular and Molecular Medicine Leuven Cancer Institute (LKI) KU Leuven Belgium

2. Laboratory of Molecular Bacteriology Department of Microbiology and Immunology Rega Institute for Medical Research KU Leuven Belgium

3. Center for Medical Biotechnology Department of Biochemistry VIB‐UGent Ghent University Belgium

4. Preclinical Models and New Therapeutic Agents Unit Regina Elena National Cancer Institute Rome Italy

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.14324

Reference74 articles.

1. Multiple Functions of BCL-2 Family Proteins

2. Bcl-2 proteins and calcium signaling: complexity beneath the surface

3. Apoptosis Regulation at the Mitochondrial Outer Membrane

4. Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

5. The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update

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