Synthesis and Biological Evaluation of New Eugenol Mannich Bases as Promising Antifungal Agents

Author:

Abrão Pedro Henrique O.1,Pizi Rafael B.1,de Souza Thiago B.1,Silva Naiara C.2,Fregnan Antonio M.1,Silva Fernanda N.1,Coelho Luiz Felipe L.2,Malaquias Luiz Cosme C.2,Dias Amanda Latercia T.2,Dias Danielle F.3,Veloso Marcia P.1,Carvalho Diogo T.1

Affiliation:

1. Laboratório de Pesquisa em Química Farmacêutica; Faculdade de Ciências Farmacêuticas; Universidade Federal de Alfenas; Rua Gabriel Monteiro da Silva Alfenas MG 700 Brazil

2. Departamento de Microbiologia e Imunologia; Instituto de Ciências Biomédicas; Universidade Federal de Alfenas; Rua Gabriel Monteiro da Silva 700 Alfenas Brazil

3. Laboratório de Fitoquímica e Química Medicinal; Instituto de Química; Universidade Federal de Alfenas; Rua Gabriel Monteiro da Silva Alfenas MG 700 Brazil

Funder

Fapemig, Brazil

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference44 articles.

1. Design, synthesis, and antifungal activity of triazole and benzotriazole derivatives;Rezaei;Eur J Med Chem,2009

2. Epidemiology of invasive candidiasis: a persistent public health problem;Pfaller;Clin Microbiol Rev,2007

3. Active surveillance cultures in critically ill patients: pathogens, patterns, and correlation with eventual bloodstream infections;Soroksky;Isr Med Assoc J,2014

4. Anidulafungin versus fluconazole for invasive candidiasis;Reboli;N Engl J Med,2007

5. Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance;Krcmery;J Hosp Infect,2002

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