Supraspinal melatonin MT <sub>2</sub> receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors-Reference-Cited by-同舟云学术

Supraspinal melatonin MT ₂ receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors

Published:2022-09-07 Issue:4 Volume:73 Page:
ISSN:0742-3098
Container-title:Journal of Pineal Research
language:en
Short-container-title:Journal of Pineal Research

Author:

Posa Luca¹²^ORCID,De Gregorio Danilo¹³,Lopez‐Canul Martha¹,He Qianzi¹,Darcq Emmanuel⁴,Rullo Laura⁵,Pearl‐Dowler Leora¹,Luongo Livio⁶,Candeletti Sanzio⁵,Romualdi Patrizia⁵,Kieffer Brigitte Lina⁴,Gobbi Gabriella¹²⁷^ORCID

Affiliation:

1. Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University Health Center McGill University Montreal Quebec Canada

2. Alan Edwards Centre for Research on Pain McGill University Montreal Quebec Canada

3. Division of Neuroscience Vita‐Salute San Raffaele University Italy Milano

4. Department of Psychiatry, School of Medicine, Douglas Hospital Research Center McGill University Quebec Montreal Canada

5. Department of Pharmacy and Biotechnology (FaBiT) Alma Mater Studiorum—University of Bologna Bologna Italy

6. Department of Experimental Medicine University of Campania “Luigi Vanvitelli” Naples Italy

7. McGill University Health Center (MUHC) Montreal Quebec Canada

Funder

Fondation Brain Canada

CQDM

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Endocrinology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jpi.12825

Reference67 articles.

1. Analgesic effects of melatonin: a review of current evidence from experimental and clinical studies

2. Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain

3. Melatonin reduces formalin-induced nociception and tactile allodynia in diabetic rats

4. Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription

5. Antinociceptive properties of selective MT2 melatonin receptor partial agonists

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