SARS‐CoV ‐2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes

Author:

de Oliveira Lilian Gomes12,de Souza Angelo Yan12,Yamamoto Pedro12,Carregari Victor Corasolla3,Crunfli Fernanda3,Reis‐de‐Oliveira Guilherme3,Costa Lícia3,Vendramini Pedro Henrique3,Duque Érica Almeida4,dos Santos Nilton Barreto4,Firmino Egidi Mayara5,Paiva Isadora Marques5,Almeida Glaucia Maria6,Sebollela Adriano6,Polonio Carolina Manganeli12,Zanluqui Nagela Ghabdan12,de Oliveira Marília Garcia1,da Silva Patrick12,Davanzo Gustavo Gastão7ORCID,Ayupe Marina Caçador8,Salgado Caio Loureiro8,de Souza Filho Antônio Francisco9ORCID,de Araújo Marcelo Valdemir9,Silva‐Pereira Taiana Tainá9,de Almeida Campos Angélica Cristine10,Góes Luiz Gustavo Bentim10,dos Passos Cunha Marielton10,Caldini Elia Garcia11,D'Império Lima Maria Regina12,Fonseca Denise Morais8,de Sá Guimarães Ana Márcia9,Minoprio Paola Camargo10,Munhoz Carolina Demarchi4,Mori Cláudia Madalena Cabrera13,Moraes‐Vieira Pedro Manoel7,Cunha Thiago Mattar5,Martins‐de‐Souza Daniel3141516,Peron Jean Pierre Schatzmann1217ORCID

Affiliation:

1. Neuroimmune Interactions Laboratory Institute of Biomedical Sciences, Department of Immunology, University of São Paulo São Paulo SP Brazil

2. Neuroimmunology of Arboviruses Laboratory, Scientific Platform Pasteur‐USP University of São Paulo São Paulo SP Brazil

3. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology Institute of Biology, University of Campinas (UNICAMP) Campinas SP Brazil

4. Department of Pharmacology, Institute of Biomedical Sciences University of São Paulo São Paulo Brazil

5. Center for Research in Inflammatory Diseases (CRID) Department of Pharmacology—Ribeirão Preto Medical School—University of São Paulo Ribeirão Preto Brazil

6. Department of Biocehmistry and Immunology, Ribeirão Preto Medical School University of São Paulo Ribeirão Preto Brazil

7. Laboratory of Immunometabolism, Department of Genetics, Evolution, Microbiology and Immunology Institute of Biology, University of Campinas Campinas Brazil

8. Laboratory of Mucosal Immunology Department of Immunology—Institute of Biomedical Sciences, University of Sao Paulo São Paulo Brazil

9. Laboratory of Applied Research in Mycobacteria, Department of Microbiology Institute of Biomedical Sciences, University of São Paulo São Paulo SP Brazil

10. Scientific Platform Pasteur – USP University of São Paulo São Paulo SP Brazil

11. Laboratory of Cellular Biology (LIM 59), School of Medicine University of São Paulo São Paulo SP Brazil

12. Department of Immunology University of São Paulo São Paulo SP Brazil

13. Department of Pathology, School of Veterinary Medicine and Animal Science University of Sao Paulo São Paulo SP Brazil

14. Experimental Medicine Research Cluster (EMRC) University of Campinas Campinas SP Brazil

15. D'Or Institute for Research and Education (IDOR) São Paulo SP Brazil

16. Instituto Nacional de Biomarcadores em Neuropsiquiatria (INBION), Conselho Nacional de Desenvolvimento Científico e Tecnológico São Paulo SP Brazil

17. Immunopathology and Allergy Post Graduate Program, School of Medicine University of São Paulo São Paulo SP Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Laboratório Nacional de Nanotecnologia

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

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