Egr1 mediates retinal vascular dysfunction in diabetes mellitus via promoting p53 transcription
Author:
Affiliation:
1. State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center, Sun Yat‐sen University Guangzhou China
Funder
National Natural Science Foundation of China
Publisher
Wiley
Subject
Cell Biology,Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.14225
Reference23 articles.
1. Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2. Pharmacologic Induction of Heme Oxygenase-1 Plays a Protective Role in Diabetic Retinopathy in Rats
3. Angiopoietin 2 Induces Pericyte Apoptosis via α3β1 Integrin Signaling in Diabetic Retinopathy
4. The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and fibronectin
5. Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence
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