SPG4 gene promoter regulation via Elk1 transcription factor
Author:
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.2011.07243.x/fullpdf
Reference36 articles.
1. Mutations of SPG4 are responsible for a loss of function of spastin, an abundant neuronal protein localized in the nucleus;Charvin;Hum. Mol. Genet.,2003
2. Spastin subcellular localization is regulated through usage of different translation start sites and active export from the nucleus;Claudiani;Exp. Cell Res.,2005
3. The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo;Davis;J. Neurol.,2000
4. Elk-1 interacts with neuronal microtubules and relocalizes to the nucleus upon phosphorylation;Demir;Mol. Cell. Neurosci.,2008
5. Genetics of motor neuron disorders: new insights into pathogenic mechanism;Dion;Nat. Rev. Genet.,2009
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