FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ-Reference-Cited by-同舟云学术

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FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ

Published:2006-11-17 Issue:3 Volume:101 Page:674-681
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:

Author:

Shioi Junichi,Georgakopoulos Anastasios,Mehta Pankaj,Kouchi Zen,Litterst Claudia M.,Baki Lia,Robakis Nikolaos K.

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1471-4159.2006.04391.x/fullpdf

Reference52 articles.

1. The Cytoplasmic Sequence of E-Cadherin Promotes non-Amyloidogenic Degradation of A Beta Precursors;Agiostratidou;J. Neurochem.,2006

2. A Presenilin 1 Mutation Associated With Familial Frontotemporal Dementia Inhibits Gamma-Secretase Cleavage of APP and Notch;Amtul;Neurobiol. Dis.,2002

3. Neurofibrillary Tangles but not Senile Plaques Parallel Duration and Severity of Alzheimer’s Disease;Arriagada;Neurology,1992

4. PS1 Activates PI3 K Thus Inhibiting GSK-3 Activity and tau Overphosphorylation: Effects of FAD Mutations;Baki;EMBO J.,2004

5. Presenilin Clinical Mutations can Affect Gamma-Secretase Activity by Different Mechanisms;Bentahir;J. Neurochem.,2006

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