Improvement in Pattern Separation by Regulating Neurogenesis in Hippocampal Culture

Author:

Tanaka Yukimi1,Kadokura Tomonosuke1,Isomura Takuya1,Shimba Kenta1,Kotani Kiyoshi23,Jimbo Yasuhiko4

Affiliation:

1. Graduate School of Frontier Sciences, The University of Tokyo

2. JST, PRESTO

3. Research Center for Advanced Science and Technology, The University of Tokyo

4. Graduate School of Engineering, The University of Tokyo

Publisher

Institute of Electrical Engineers of Japan (IEE Japan)

Subject

Electrical and Electronic Engineering

Reference28 articles.

1. (1) A. Marin-Burgin and A. F. Schinder : “Requirement of adult-born neurons for hippocampus-dependent learning”, Behav. Brain. Res., Vol. 227, pp. 391-399 (2012)

2. (2) A. Sahay, K. N. Scobie, A. S. Hill, C. M. O'Carroll, M. A. Kheirbek, N. S. Burghardt, A. A. Fenton, A. Dranovsky, and R. Hen : “Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation”, Nature, Vol. 472, pp. 466-470 (2011)

3. (3) C. D. Clelland, M. Choi, C. Romberg, G. D. Clemenson Jr., A. Fragniere, P. Tyers, S. Jessberger, L. M. Saksida, R. A. Barker, F. H. Gage, and T. J. Bussey : “A functional role for adult hippocampal neurogenesis in spatial pattern separation”, Science, Vol. 325, pp. 210-213 (2009)

4. (4) J. E. Cheyne, L. Grant, C. Butler-Munro, J. W. Foote, B. Connor, and J. M. Montgomery : “Synaptic integration of newly generated neurons in rat dissociated hippocampal cultures”, Mol. Cell. Neurosci., Vol. 47, pp. 203-214 (2011)

5. (5) C. L. Stephens, H. Toda, T. D. Palmer, T. B. Demise, and B. K. Ormerod : “Adult neural progenitor cells reactivate superbursting in mature neural networks”, Exp. Neurol., Vol. 234, pp. 20-30 (2012)

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