Localization of the (TTAGGG)n telomeric sequence in zebrafish chromosomes

Abstract

The distribution of the (TTAGGG)n telomeric sequence in Danio rerio (zebrafish) metaphase chromosomes was studied by fluorescence in situ hybridization. This study continues the analysis of the telomeric sequence distribution in fish and confirms that the (TTAGGG)n sequence is conserved in the telomeres of this group of vertebrates. The hybridization signals were restricted to telomeres in all the individuals analysed. With the degree of resolution currently available, no interstitial sites of the telomeric sequence were detected, which suggests that this type of hot-spot recombination site might be absent in zebrafish chromosomes.