Identification of Radioactive 17β-Estradiol-17-β-D-glucuronide and 17α-Estradiol-17-β-D-glocuronide in the Urine of the Domestic Fowl after Intramuscular Injection of [4-14C]Estrone

Abstract

Two previously uncharacterized radioactive estrogen conjugates, 17β-estradiol-17-β-D-glucuronide (3-hydroxyestra-1,3,5(10)-trien-17β-yl-β-D-glucopyranosiduronate) and 17α-estradiol-17-β-D-glucuronide (3-hydroxyestra-1,3,5(10)-trien-17α-yl-β-D-glucopyranosiduronate), have been identified in small but significant amounts in avian urine and in a ratio of approximately 2:1 after intramuscular injection of [4-14C]estrone.