Anti-mycobacterial activities of copper(II) salicylaldimine complexes derived from long-chain aliphatic amines-Reference-Cited by-同舟云学术

Anti-mycobacterial activities of copper(II) salicylaldimine complexes derived from long-chain aliphatic amines

Published:2013-11 Issue:11 Volume:91 Page:1093-1097
ISSN:0008-4042
Container-title:Canadian Journal of Chemistry
language:en
Short-container-title:Can. J. Chem.

Author:

Patterson Alyssa E.¹,Bowes Eric G.¹,Bos Allyson²,O’Neill Taryn²,Li Haoxin²,Flewelling Andrew²,Vogels Christopher M.¹,Decken Andreas³,Gray Christopher A.²,Westcott Stephen A.¹

Affiliation:

1. Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB E4L 1G8, Canada.

2. Department of Biology, University of New Brunswick, Saint John, NB E2L 4L5, Canada.

3. Department of Chemistry, University of New Brunswick, Fredericton, NB E3B 5A3, Canada.

Abstract

Twelve copper(II) Schiff base complexes derived from lipophilic amines have been prepared using either salicylaldehyde or ortho-vanillin via a microwave-assisted reaction. All complexes have been obtained elementally pure and an X-ray diffraction of an isopentyl derivative has confirmed the structure of these compounds. All complexes showed a promising degree of anti-mycobacterial activity against Mycobacterium tuberculosis, where activity seemed to increase with an increase in the length of the aliphatic chain.

Publisher

Canadian Science Publishing

Subject

Organic Chemistry,General Chemistry,Catalysis

Link

http://www.nrcresearchpress.com/doi/pdf/10.1139/cjc-2013-0274

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