Residues of antibiotics in milk: persistence and quality interference

Author:

Alves Janine F.1,Paula Guilherme H.1,Silva Rânio C.F.1,Leão Paulo V.T.1,Leão Karen M.1,Nicolau Edmar S.2,Silva Marco A.P.1

Affiliation:

1. Laboratory of Products of Animal Origin, Federal Institute of Goiás-Rio Verde College, Rio Verde, Goiás 75.901-970, Brazil.

2. Milk Quality Laboratory of the Center for Food Research of the Veterinary and Animal Science, Federal University of Goiás, Goiânia, Goiás 74690-900, Brazil.

Abstract

The objective of this study was (i) to analyze antibiotic residues, two which were beta-lactam antibiotics, one tetracycline, and one quinolone in the milk of lactating animals; (ii) to evaluate the interference of the drug ceftiofur which is considered as discard-zero. The SNAPduo™ ST Plus kit was used to evaluate the presence of beta-lactam antibiotics and tetracyclines in natural milk. Medications based on penicillin, ceftiofur, enrofloxacin, and oxytetracycline were used. As expected, the milk from control animals and animals administered with enrofloxacin did not present antibiotic residue because it is not one of the classes detected by the SNAPduo™ ST Plus kit, and thus it was used to prove the efficiency of the test. Ceftiofur, known as a “discard-zero” antibiotic, tested positive for the SNAPduo™ ST Plus kit and the BetaStar Combo® “S” test. Chemical residues were detected in cow’s milk treated with different groups of antibiotics after the withdrawal time indicated in the package inserts of the medicines used.

Publisher

Canadian Science Publishing

Subject

Animal Science and Zoology,Food Animals

Reference32 articles.

1. Ocitocina exógena e a presença do bezerro sobre a produção e qualidade do leite de vacas mestiças

2. Brazil, Ministry of Agriculture, Livestock and Supply. Normative Instruction nº62, of December 29. 2011. Approves the technical regulation on the production, identity and quality of milk type A, the technical regulation on identity and quality of refrigerated raw milk, the technical regulation on the identity and quality of pasteurized milk and the technical regulation on the collection of refrigerated raw milk and its transport in bulk, in accordance with the annexes of this normative instruction. Official Journal of the Union, Brasília, DC, Brazil.

3. Carraro, C.N.M. 1999. Residues of antibiotics in milk from treated and untreated quarters of dairy cows using microbial and enzymatic inhibition methods. Dissertation (Master in Food Technology), Chemical Technology Sector, Federal University of Paraná, Curitiba, 89 pp.

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