Decreased Gene Expressions of Insulin Signal Molecules in Canine Hyperadrenocorticism

Author:

NOZAWA Satoshi12,ODA Hitomi2,AKIYAMA Ran2,UEDA Kaori2,SAEKI Kaori2,SHONO Saori2,MARUYAMA Natsuki2,MURATA Atsuki1,TAZAKI Hiroyuki1,MORI Akihiro2,MOMOTA Yutaka2,AZAKAMI Daigo2,SAKO Toshinori2,ISHIOKA Katsumi2

Affiliation:

1. Laboratory of Biomolecular Chemistry, School of Veterinary Medicine, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonan-cho, Musashino-shi, Tokyo 180–8602, Japan

2. Department of Veterinary Nursing, School of Veterinary Nursing and Technology, Faculty of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonan-cho, Musashino-shi, Tokyo 180–8602, Japan

Publisher

Japanese Society of Veterinary Science

Subject

General Veterinary

Reference49 articles.

1. 1. Andrews, R. C. and Walker, B. R. 1999. Glucocorticoids and insulin resistance: old hormones, new targets. Clin. Sci. (Lond.) 96: 513–523.

2. Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

3. 4. Burén, J., Liu, H. X., Jensen, J. and Eriksson, J. W. 2002. Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B in primary cultured rat adipocytes. Eur. J. Endocrinol. 146: 419–429.

4. Insulin action and signalling in fat and muscle from dexamethasone-treated rats

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