Europe Approves First Immunotherapy plus PARP Inhibitor Combination in Endometrial Cancer

Author:

,Hofland PeterORCID

Abstract

The European Commission has approved durvalumab (Imfinzi®; AstraZeneca)* and olaparib (Lynparza®; AstraZeneca)**, the first immunotherapy and PARP inhibitor combination, for the treatment for certain patients with primary advanced or recurrent endometrial cancer.

Publisher

Sunvalley Communication

Reference19 articles.

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3. [3] Oaknin A, Bosse TJ, Creutzberg CL, Giornelli G, Harter P, Joly F, Lorusso D, Marth C, Makker V, Mirza MR, Ledermann JA, Colombo N; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Endometrial cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2022 Sep;33(9):860-877. doi: 10.1016/j.annonc.2022.05.009. Epub 2022 Jun 8. PMID: 35690222.

4. [4] Aghajanian C, Filiaci V, Dizon DS, Carlson JW, Powell MA, Secord AA, Tewari KS, Bender DP, O'Malley DM, Stuckey A, Gao J, Dao F, Soslow RA, Lankes HA, Moore K, Levine DA. A phase II study of frontline paclitaxel/carboplatin/bevacizumab, paclitaxel/carboplatin/temsirolimus, or ixabepilone/carboplatin/bevacizumab in advanced/recurrent endometrial cancer. Gynecol Oncol. 2018 Aug;150(2):274-281. doi: 10.1016/j.ygyno.2018.05.018. Epub 2018 May 24. PMID: 29804638; PMCID: PMC6179372.

5. Genetic susceptibility to endometrial cancer: Risk factors and clinical management;Dork;Cancers,2020

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