Pharmacodynamics of Single Doses of the Novel Immunosuppressant FTY720 in Stable Renal Transplant Patients

Author:

Budde Klemens,L. Schmouder Robert,Nashan Bjorn,Brunkhorst Reinhard,W. Lücker Peter,Mayer Thomas,Brookman Laurence,Nedelman Jerry,Skerjanec Andrej,Böhler Torsten,Neumayer Hans-Hellmut

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Reference24 articles.

1. Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: discovery of a novel immunosuppressant, FTY720;Adachi;Bioorg Med Chem,1995

2. Fungal metabolites. Part II. A potent immunosuppressive activity found in Isaria Sinclairii metabolite;Fujita;J Antibiot (Tokyo),1994

3. A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation;Suzuki;Transplantation,1996

4. FTY720, a novel immunosuppressant possessing unique mechan-isms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A;Hoshino;Transplant Proc,1996

5. Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY720, in rat small bowel transplantation;Mitsusada;Transpl Int,1997

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